Synadentix review: oral support with enzymes
Synadentix is a soft-tablet supplement made to support oral health. Its 400 mg blend pairs calcium with beta-glucanase and dextranase among 10 ingredients. No other product in our oral health support ranking lists those two enzymes on its label.12
Why it stands out
Strong teeth and gums. The brand says its soft tablets support the oral microbiome for strong teeth and gums.6
Calcium plus two enzymes. The formula includes calcium, beta-glucanase and dextranase in a 400 mg proprietary blend.2
One soft tablet. The label starts at 1 soft tablet a day, held in your mouth for 30 seconds before swallowing.2
What's inside
How to take it
- Directions
- "Take one soft tablet one or up to two times a day, or as recommended by your healthcare provider, ideally after brushing teeth or using mouthwash. Hold tablet in mouth for 30 seconds to dissolve and then swallow."2
Supplement Facts
Serving size 1 tablet
Servings per container 30
| Amount per serving | Amount | % Daily Value |
|---|---|---|
| Proprietary Blend | 400 mg | † |
| Guava Fruit Powder, Micro Crystalline Hydroxyapatite Complex, Beta-glucanase (endo-1,3(4)-), Dextranase, Amylase, Lactoperoxidase, Glucose oxidase, Amyloglucosidase, Lysozyme, Lactoferrin | ||
† Daily Value not established.
Other ingredients: Xylitol, Microcrystalline Cellulose (AceCel 200), Magnesium Stearate, Natural Flavoring.
As printed on the label2
What each ingredient is
- Calcium
- A mineral the body needs to build and maintain strong bones, which the NIH says the body also needs for muscles to move and nerves to carry messages.8
- Beta-glucanase
- Beta-glucanase is an enzyme that breaks down beta-glucans into smaller pieces.9
- Dextranase
- Dextranase is an enzyme that breaks down dextran.10
- Lactoperoxidase
- Lactoperoxidase is an enzyme derived from cow's milk.12
- Glucose oxidase
- Glucose oxidase is an enzyme used in food manufacturing.13
- Amyloglucosidase
- Amyloglucosidase is an enzyme that can be derived from Rhizopus niveus.14
- Lactoferrin
- Bovine lactoferrin is a protein naturally found in cow's milk.16
Who it's for
Made for
- Adults looking for daily oral health support
- People who prefer soft tablets
- Anyone who wants 90 days to decide
Ask your doctor first if
- You are pregnant or nursing
- You take medication or have a condition
- You are under 18
"Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement"
A supplement is not a medicine. Keep taking what your clinician prescribed, and ask before you add anything new.
Prices and bundles
Lowest price per bottle
6 bottles
180-day supply
$49a bottle
$294 total1
- Shipping
- Free in the US
- Bonus
- Three free e-books
How we rank
How we rank: what shoppers buy and keep after refunds, price, guarantee, order terms, checked against product labels and sellers' own pages.
Partners pay us when you buy through our links. That can affect which products we feature and where they appear.
AI drafts our pages from listed sources, figures are checked against them, and we have not tried the products.
Prices checked About these prices
- Prices as the brand's order page showed them on Oct 11, 2026. Its order page shows the current price before you pay.
- Shipping as the order page showed it, to a visitor outside the US. US visitors can see a different shipping line.
- The label allows a second serving a day, which makes a bottle last half as long.
The guarantee
90 days
from the day your package arrives, and empty bottles count134
"Your order today is covered by our iron-clad 90-day 100% money-back guarantee. If you are not impressed with the results, then just write to us and we’ll refund every single cent."
How to get a refund
- 1Ask for a refund within 90 days of the day your package arrives. Email contact@synadentix-product.com.
- 2Send the bottles back, even empty ones, to the address on the return policy page. You pay the return shipping.
From the return policy
- "After your purchase, you have 90 days from the moment you get your package to explore the benefits of this amazing product."
- "Send all the bottles back to us (no matter if they are empty or not) at the below address. It doesn’t matter if the bottles are opened or not."
- "Please keep in mind that we do not support the return shipping costs."
How to order
Step by step
- 1Pick a bundle in the price table. Its button opens Synadentix's order page.
- 2Choose the same bundle there. The order page opens the secure checkout.
- 3Enter your shipping address and payment details. The checkout shows the price and the shipping before you pay.
- 4Pay once. There is no subscription and no later charge.
- 5After payment, the checkout opens a follow-up offer page from the brand. Your bottles ship to the address you entered.
- ThenThe bonuses that come with 6 bottles cost nothing extra. Delivery terms are on the brand's shipping policy page.15
Where to buy
Synadentix comes from the brand's own store at thesynadentix.com, which checks out on BuyGoods. That store is where the 90-day guarantee applies, and it is where every button on this page goes.
The 90-day guarantee on this page is the brand store's own policy. See the bundles
How it compares
The same for all three: $49 a bottle at the lowest, soft tablets, 1 tablet a day and a one-time payment.
 This reviewSynadentix |  #3 in our rankingProDentim |  #4 in our rankingDentiCore | |
|---|---|---|---|
| Our score | 9.4 out of 10 | 9.1 out of 10 | 8.9 out of 10 |
| Money-back | 90 days | 60 days | 60 days |
| On the label | 10 in a 400 mg blend, no amounts12 | 2 with amounts, 3 in a 20 mg blend17 | 4 with amounts, 4 in a 120 mg blend18 |
| Key ingredients | Guava, calcium, beta-glucanase | Probiotics, inulin, streptococcus salivarius | Chromium, calcium, iodine |
| Shipping | Free in the US on 3 and 6 bottles | Free in the US on 3 and 6 bottles | Free in the US on 6 bottles |
| Read | See the bundles | Read the ProDentim review | Read the DentiCore review |
Questions
What is Synadentix advanced oral support?
Synadentix is a soft-tablet supplement made to support oral health. The brand says it supports the oral microbiome for strong teeth and gums. Its formula includes calcium, beta-glucanase and dextranase.
Does Synadentix work?
Synadentix is made to support oral health, with calcium, beta-glucanase and dextranase in its formula. Orders from the brand's store have a 90-day money-back guarantee from delivery, giving you time to decide.
Is Synadentix a chewable tablet?
Synadentix comes as soft tablets, with label directions to dissolve one in your mouth for 30 seconds, then swallow. Take 1 tablet 1 or up to 2 times a day, ideally after brushing your teeth or using mouthwash.
What ingredients are in Synadentix?
Synadentix lists 10 ingredients in a 400 mg proprietary blend, including guava fruit powder, a calcium complex, beta-glucanase and dextranase. Other blend ingredients include amylase, lactoperoxidase, glucose oxidase, amyloglucosidase, lysozyme and lactoferrin. The label gives the blend total, not individual ingredient amounts.
How much does Synadentix cost?
Synadentix costs $49 to $79 a bottle at the brand's store. Two bottles cost $158, three cost $207 and six cost $294. The order page shows the current price and shipping before you pay.
Where can I buy Synadentix?
Buy Synadentix from the brand's own store at thesynadentix.com, which checks out through BuyGoods. That store is where the 90-day guarantee applies. The buttons on this page open Synadentix's order page.
Is Synadentix legit?
Synadentix's label names its distributor as Synadentix at 285 Northeast Ave, Tallmadge, OH 44278, United States. Its own store checks out through BuyGoods, a Delaware company in Wilmington. Store orders carry a 90-day money-back guarantee from delivery, with empty bottles accepted for returns.
What should I look for in Synadentix reviews?
Look for the published label, current prices and refund terms. This page covers Synadentix's ingredients, directions, prices and guarantee. You can ask the brand questions at contact@synadentix-product.com.
How do I contact Synadentix about complaints?
Email contact@synadentix-product.com for Synadentix complaints or order support. Refund requests must be made within 90 days of delivery, and all bottles must be returned, including empty ones. You pay return shipping.
Can I try Synadentix with a money-back guarantee?
Yes, orders from the brand's store have a 90-day money-back guarantee starting when your package arrives. Request a refund at contact@synadentix-product.com and return all bottles, even empty ones, to the address on the return policy page. You pay return shipping.
Is Synadentix a subscription?
No, Synadentix orders are a one-time payment. There is no subscription or later charge.
Can I take Synadentix with medication?
Ask a clinician before starting Synadentix if you take medication. The label also says people who are pregnant, nursing, under 18 or have a known medical condition should seek medical advice before use.
Sources
How we made this page
AI drafts our pages from listed sources, figures are checked against them, and we have not tried the products.
What shoppers buy and keep after refunds, price, guarantee, order terms, checked against product labels and sellers' own pages. How we pick
The FDA line
These statements have not been evaluated by the FDA. Synadentix is a dietary supplement, not a medicine.
What changed
- Updated: ingredients, the comparison and sources.
- Published
- 1Synadentix's order pageBundles, bonuses, shipping, the guarantee and the FAQthesynadentix.com/startchecked
- 2Supplement Facts label, as the brand publishes itServing, ingredients and amounts, directions, warnings, distributorthesynadentix.com/staticschecked
- 3Return policyHow to return, who pays shipping, the return addressthesynadentix.com/helpchecked
- 4Contact pagePhone and emailthesynadentix.com/helpchecked
- 5Shipping policythesynadentix.com/helpchecked
- 6Synadentix's sales pageWhat the brand says it is made to support. We do not link it: it is a sales pageNo public pagechecked
- 7NIH National Library of Medicine, Medical Subject Headings, Psidiummeshb.nlm.nih.gov/recordchecked
- 8NIH Office of Dietary Supplements, Calcium, Fact Sheet for Consumersods.od.nih.gov/factsheetschecked
- 9EFSA Journal (2025), scientific opinion 9770efsa.onlinelibrary.wiley.com/doichecked
- 10EFSA Journal (2020), scientific opinion 6309efsa.onlinelibrary.wiley.com/doichecked
- 11NIH National Cancer Institute Thesaurus, Amylaseevsexplore.semantics.cancer.gov/evsexplorechecked
- 12NIH National Library of Medicine, Medical Subject Headings, Lactoperoxidasemeshb.nlm.nih.gov/recordchecked
- 13EFSA Journal (2025), scientific opinion 9290efsa.onlinelibrary.wiley.com/doichecked
- 14US Code of Federal Regulations, 21 CFR 173.110, Amyloglucosidase derived from rhizopus niveusecfr.gov/currentchecked
- 15EFSA Journal (2025), scientific opinion 9726efsa.onlinelibrary.wiley.com/doichecked
- 16EFSA Journal (2012), scientific opinion 2811efsa.onlinelibrary.wiley.com/doichecked
- 17ProDentim's order pageForm, serving, label, guarantee, shipping and prices on the order pagetheprodentim.com/startchecked
- 18DentiCore's order pageForm, serving, label, guarantee, shipping and prices on the order pagethedenticore.com/startchecked