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Glucose oxidase explained: what it is and its source

Glucose oxidase is an enzyme that can be produced using genetically modified Aspergillus oryzae. EFSA (the European Food Safety Authority) says the enzyme is purified and concentrated by filtration that retains its protein. One product we reviewed lists glucose oxidase, and none prints its individual amount.

By HowNook's Health desk · Updated

In the products we reviewed
1, its label does not print the amount

What glucose oxidase is

  • Glucose oxidase can be produced using genetically modified Aspergillus oryzae.3
  • The enzyme is purified and concentrated by filtration that retains its protein.1
  • The Aspergillus tubingensis preparation loses activity above 60°C after five minutes of heating and has no remaining activity at 77°C.1

How much glucose oxidase each product gives

Per serving, as each label prints it

Amount not printed: the dashed line shows the most it can be, the whole blend

SynadentixNot printed · at most 400 mg

Before you take it

Ask a doctor first

  • People with almond allergy may have allergic reactions to glucose oxidase made using Penicillium rubens.2

These statements have not been evaluated by the FDA. A supplement is not a medicine.

The product we reviewed that lists glucose oxidase

ProductForm and servingGlucose oxidase per servingOur scorePrice a bottleBuy
Synadentix#2 in oral health supportSoft tablets1 tabletNot printedIn a 400 mg proprietary blend9.4$49Check price
Prices checked Oct 11, 2026

Questions people ask

What is glucose oxidase?

Glucose oxidase is an enzyme that can be produced using genetically modified Aspergillus oryzae. EFSA (the European Food Safety Authority) says it is purified and concentrated by filtration that retains its protein.

Is glucose oxidase an enzyme?

Yes, glucose oxidase is an enzyme. EFSA says the Aspergillus tubingensis preparation loses activity above 60°C after five minutes of heating and has no remaining activity at 77°C.

Which supplements we reviewed contain glucose oxidase?

Synadentix is the only supplement we reviewed that lists glucose oxidase. It comes in soft tablets, with a serving of 1 tablet.

How much glucose oxidase is in Synadentix?

The individual amount of glucose oxidase in Synadentix is not printed. It is listed inside a 400 mg proprietary blend.

What should I check before taking glucose oxidase?

An almond allergy is a reason to ask a clinician before starting glucose oxidase. People with almond allergy may have allergic reactions to glucose oxidase made using Penicillium rubens.

Sources

The products, amounts and prices come from each product's label and checkout, as its review shows them. AI drafts our pages from listed sources, figures are checked against them, and we have not tried the products.

  1. 1EFSA Journal (2025), scientific opinion 9290efsa.onlinelibrary.wiley.com/doichecked
  2. 2EFSA Journal (2025), scientific opinion 9494efsa.onlinelibrary.wiley.com/doichecked
  3. 3EFSA Journal (2026), scientific opinion 10209efsa.onlinelibrary.wiley.com/doichecked