Pine bark extract explained: what it is and side effects

The extract comes from pine tree bark, commonly the maritime pine Pinus pinaster, and the NIH says its plant compounds with antioxidant activity are thought to be its active ingredients. The NIH names a typical dose of 100 to 400 mg daily. One product we reviewed lists pine bark extract, and none prints its individual amount.

PiPine bark extractPiPine bark extract
What it is
Plant
Amounts the NIH names
The typical dose of pine bark extract is 100 to 400 mg daily.
In the products we reviewed
1, its label does not print the amount

What pine bark extract is

  • Pine bark extract comes from pine tree bark.1
  • Pinus pinaster is a maritime pine commonly used to make pine bark extract.1
  • Pine bark contains plant compounds, carbohydrates, sugars, minerals, and vitamins.1
  • Pine bark is rich in plant compounds with antioxidant activity that are thought to be its active ingredients.1
  • Pycnogenol is a commercial Pinus pinaster extract standardized to contain 70% procyanidins.1
  • Some supplements combine pine bark with other ingredients without providing its concentration.1

How much pine bark extract each product gives

Per serving, as each label prints it, against the amounts the NIH names

NIH: 100 mg to 400 mg per dose

Amount not printed: the dashed line shows the most it can be, the whole blend

CellucareNot printed · at most 528 mg

Before you take it

Ask a doctor first

  • One report of muscle injury was possibly associated with a higher-than-recommended dose.1

These statements have not been evaluated by the FDA. A supplement is not a medicine.

The product we reviewed that lists pine bark extract

ProductForm and servingPine bark extract per servingOur scorePrice a bottleBuy
Cellucare#4 in blood sugar supportCapsules1 capsuleNot printedIn a 528 mg proprietary blend9.4$49Check price
Prices checked Sep 30, 2026

Questions people ask

What is pine bark extract?

Pine bark extract comes from pine tree bark, commonly the maritime pine Pinus pinaster. The NIH says pine bark contains plant compounds, carbohydrates, sugars, minerals, and vitamins.

What does pine bark extract do?

Pine bark is rich in plant compounds with antioxidant activity, according to the NIH. These compounds are thought to be its active ingredients.

How much pine bark extract should I take per day?

The NIH names 100 to 400 mg daily as the typical dose of pine bark extract. Ask a clinician before starting.

Is pine bark extract the same as Pycnogenol?

Pycnogenol is a specific commercial pine bark extract made from Pinus pinaster. The NIH says it is standardized to contain 70% procyanidins.

What side effects are reported for pine bark extract?

One report described muscle injury possibly associated with a higher-than-recommended dose of pine bark extract. Ask a clinician before starting.

Which products we reviewed contain pine bark extract?

Cellucare is the only product we reviewed that lists pine bark extract. Its amount is not printed separately because it is inside a 528 mg proprietary blend. Cellucare comes in capsules, with a serving of 1 capsule.

Sources

The products, amounts and prices come from each product's label and checkout, as its review shows them. AI drafts our pages from listed sources, figures are checked against them, and we have not tried the products.

  1. 1NIH LiverTox, Pine Barkncbi.nlm.nih.gov/bookschecked